Flowing Towards Tomorrow
Do it all with TekFlow Labs
Flowing Towards Tomorrow: Innovating Chemistry, Redefining Boundaries. Discover the Future of Chemical Engineering with Tekflow Labs.
About Us
Young & Nimble, TEKFLOW LABS Pvt. Ltd. is a privately held Project Management company founded by a team of Pharma professionals with 8+ years of experience in flow chemistry process optimization We are process intensification enthusiasts, with background of chemical engineering having excellent academic records, sound technology expertise and implementation skills
We are process intensification enthusiasts, with background of chemical engineering having excellent academic records, sound technology expertise and implementation skills.
To make conventional chemical production routes greener, safer, smaller, faster and cost-effective.
To make process intensification and flow chemistry, available, applicable and affordable for chemical industries and create a greener impact over Indian Chemical Industry
We are proud to collaborate with innovative and forward-thinking companies. One of our esteemed Partner is Flowrhex, a leader in the field of flow chemistry technology.
Flowrhex is revolutionizing flow chemistry with their cutting-edge technology. We are thrilled to support and enhance their mission through our expertise in process intensification and chemical process development.
Services we offer
1. Technology Transfer
Tekflow labs offers Technology Transfer (TT) to its clients in the pharmaceutical/chemical industry via the process of transferring the technology and knowledge to its clients about the manufacturing of their drugs through continuous process. This process is often necessary when our clients want to bring a new drug to market and needs to scale up production to meet demand.
There are several steps involved in the technology transfer process and these may include:
- Identifying the appropriate technology and equipment needed for production
- Establishing a detailed process flow diagram
- Developing process control strategies and scale-up methods
- Transferring the process to the receiving organization through training, documentation, and validation
- Ensuring that the receiving organization is capable of consistently producing the drug to the required quality standards
2. Process intensification
We provide dedicated flow technology equipment’s at every single stage as per the client requirements whether it is for pilot or plant level, we efficiently conduct route scouting, rapid process development, optimization of reaction conditions for scale-up of materials.
Our continuous flow processing capabilities offer unique advantages compared with batch processes, resulting in faster, safer and more robust material production with higher selectivity of desired products.
Our expert equipment and capabilities include:
- Tubular reactors and static mixers to handle multiple batch sizes (mg to kilogram scale)
- Plate type micro reactor for Reaction that require micro mixing
- Pilot and commercial units for hydrogenation
- Custom build reactors for high temperature reactions (100 to 300°C)
- Ability to scale extreme temperatures (reactions from -80 °C to RT using tubes and tube-in-tube reactors)
- Ability to scale hazardous chemistry
3. CDMO Services for Clients
Our chemists are leading experts in organic chemistry and our advanced facilities provide the capacity and quality systems to meet your small molecule APIs and intermediates needs from pre-clinical to commercialization and into late life cycle.
We place a strong emphasis on customer satisfaction by delivering the best service with the best people. Our teams from lab to pilot & from pilot to production are dedicated to deliver a full service to our partners, from lab scale to pilot scale (5 – 50 kg/batch) and to production scale (100+ kg/batch).
Overview of Services with dedicated continuous flow technology:
- High Potency APIs
- Cryogenic & High-Pressure Reactions
- High Energy Chemistries
- Multistep Synthesis
- High-Pressure Hydrogenation
- Oxidation Reactions
- Nitration and Sulfonation
- Diazotization and Azide Chemistry
- Process Development and Optimization
Our Business Model
TEKFLOW Continuous Flow Chemistry
- Demonstration of process
- 3 - 6 weeks Proof of Concept
- Robustness of process testing
- Define process limits/failure points
- Preparation of process description
- 4-6 weeks
- 1-2 kg demo batch
- Cost analysis conducted
- 2-5 weeks
- mT/week output possible with correct reactor design
Process Intensification and Flow Chemistry
Flow chemistry is a modern technique used for synthesis that utilizes pumps, tubing, and reactor coils rather than traditional round-bottomed flasks found in batch applications, allowing for faster reactivity, increased mass/heat transfer, increased safety, it involves running chemical reactions in a continuous flow of reagents through a reactor, as opposed to traditional batch chemistry where reactants are mixed and allowed to react in a single vessel.
Flow chemistry has several advantages, including improved control over reaction parameters, safety, and scalability. In terms of "doable" and "demanding" molecules in the market, the applicability of flow chemistry depends on various factors, such as the specific type of reaction and the complexity of the molecules involved. Continuous Flow Chemistry opens up the possibility to access new synthetic routes to a given intermediate or API which are not achievable in conventional batch mode due to issues around safety, impurity formation and the instability of reactive intermediates.
TEKFLOW Continuous Flow Chemistry
Choosing Continuous flow offers a variety of advantages over traditional batch processing. There are five strategic drivers towards choosing Flow Chemistry over traditional batch with TEKFLOW.
Faster Reactions
Typically, under continuous flow, reactions are faster due to improved mixing and better heat transfer resulting from the smaller-scale architectures offering higher surface area to volume compared with traditional batch vessels. Reaction rate is also increased by the ability to access temperatures and pressures inaccessible in batch, with potential for automated reaction screening.
Safer Reactions
Continuous flow is inherently safer due to the small volumes reacting at any one time, with reactive intermediates/hazardous reagents handled in situ.
Challenging Reactions
Reactions which are difficult to scale up in batch, such as high pressure, high energy, oxidation, or photochemical, can be performed under continuous flow.
Product Quality
Tight controls of stoichiometry improve product quality. In-line monitoring can identify a change in product quality and allow for diversion to waste, eliminating failed batches. The ability to perform a controlled quench means a simple work-up with a reduced number of handling steps is typically required.
Smaller Footprints
Equipment is much smaller than typical batch vessels, with the ability to tailor the flow rig to suit the process and produce higher unit productivity.
Meet Our Team
Here are our main contacts. Feel free to reach out to any of us directly.
Chief Technology Officer
surya@tekflowlabs.com
+91 6281733404
LinkedIn
Chief Scientist
info@tekflowlabs.com
+91 97049 56230
LinkedIn
Business Development Head
admin@tekflowlabs.com
+491798154968
LinkedInDelivering process intensified solutions to transform conventional chemical production into greener, safer, more compact, faster, and cost-effective methods
Contact Us
Registered Office
Regd. Address: 6-84, Maharajpet, Gopularam, Hyderabad, Telangana 501203
+91 6281733404
Contact Us
Lab Office
Road no 11, Plot no: 22-23, ALEAP Industrial Estate, Near Pragathi Nagar, Kukatpally, Hyderabad 500072, Telangana, India.
+91 6281733404